Addictive Learning That Sticks

Dr. Genega is an Assistant Professor of Pathology at Harvard Medical School and is the Associate Director of the Surgical Pathology Fellowship at the Beth Israel Deaconess Medical Center, Boston, MA.

Education: 
University of Notre Dame          B.S.      1984-1988        Science Pre-Professional
New Jersey Medical School       M.D.     1989-1993         Medicine

Positions and Employment:
1993-1997          Pathology Resident (Anatomic & Clinical),
                              New York University Medical Center, New York, NY
1995-1997         Pathology Chief Resident (Anatomic & Clinical),
                              New York Univ. Medical Center, New York, NY
1997-1998         Oncologic Pathology Fellow, Memorial Sloan-Kettering Cancer Center, NY
1998-1999         Genitourinary Pathology Fellow, Memorial Sloan-Kettering Cancer Ctr, NY
1999-2002         Assistant Professor of Pathology, University of Pennsylvania, PA
1999-2002         Staff Pathologist, University of Pennsylvania Medical Center, PA
2002-2007         Instructor, Harvard Medical School, Boston, MA
2002-present     Staff Pathologist, Beth Israel Deaconess Medical Center, Boston, MA
2007-present     Assistant Professor of Pathology, Harvard Medical School, Boston, MA
2007-present     Associate Director, Surgical Pathology Fellowship,
                              Beth Israel Deaconess Medical Center

Professional Memberships:
1993-present      Member, American Medical Association
1999-present      Member, United States & Canadian Academy of Pathology
1999-2001          Member, International Society for Urological Pathology
2000-present      Member, College of American Pathologists
2000-2002          Member, Philadelphia Pathology Society
2000-2001          Member, Resident Advisory Committee, University of Pennsylvania
                                 Medical Center, Philadelphia, PA
2005-present      Member, Masschusetts Pathology Society, Boston, MA

Other Positions and Activities:
2003-2005          Co-Director, Ardais Tissue Bank, Department of Pathology,
                                  Beth Israel Deaconess Medical Center, Boston, MA
2003-2008         Medical Director, Histology Laboratory, Department of Pathology,
                                  Beth Israel Deaconess Medical Center, Boston, MA
2003-present     Medical Director, Cutting Room, Department of Pathology,
                                  Beth Israel Deaconess Medical Center, Boston, MA
2004-present     Member, Residency Training Committee, Department of Pathology,
                                  Beth Israel Deaconess Medical Center, Boston , MA

Awards and Honors:
2005     Golden Microscope Award for Excellence in Teaching, Department of Pathology,
                                  Beth Israel Deaconess Medical Center, Boston, MA
2008     Certificate of Merit, 97th Annual Meeting of the United States and Canadian
                                  Academy of Pathology

Selected Peer-Reviewed Publications (in chronological order):
1.          Demopoulos RI, Genega E, Carlson E, Vamvakas E, Mittal K: Papillary carcinoma of the endometrium: morphologic predictors of long term survival. Int J Gyn Path 1996; 5: 110-118.
2.         Taratuta E, Krinsky G, Genega E, Roche K, Genisier N: Pediatric inflammatory pseudotumor of the stomach: contrast enhanced CT and MR findings. AJR 1996; 167: 919-920.
3.         Genega E, Ittmann M, Wieczorek R, Sidhu G: Carcinosarcoma of the renal pelvis with immunohistochemistry and review of the literature. J Urol Pathol 1997; 6: 205-212.
4.         Weinstein RP, Genega EM, Dalbagni G: Splenosis mimicking transitional cell carcinomatosis: a case report. J Urol 1999; 161:1281.
5.         Hull GW, Genega EM, Sogani PC: Intravascular capillary hemangioma presenting as a solid renal mass. J Urol 1999; 162: 784-785.
6.         Genega EM, Hutchinson B, Reuter VE, Gaudin PB: Immunophenotype of high grade prostatic adenocarcinoma and urothelial carcinoma. Mod Pathol 2000; 13: 1186-1191.
7.         Charny CK, Glick RD, Genega EM, Meyers PA, Reuter VE, LaQuaglia MP: Ewing’s sarcoma/primitive neuroectodermal tumor of the ureter: a case report and review of the literature. J Pediatr Surg 2000; 35:1356-8.
8.         Buxbaum JN, Genega EM, Lazowski P, Kumar A, Tunick PA, Kronzon I, Gallo GR: Infiltrative nonamyloidotic monoclonal immunoglobulin light chain cardiomyopathy: an underappreciated manifestation of plasma cell dyscrasias. Cardiology 2000; 93: 220-8.
9.         Cohen DL, Townsend RR, Genega EM, Tomaszewski JE, Kobrin S: Dramatic recovery of renal function after six months dialysis dependence following surgical correction of total renal artery occlusion in a solitary kidney. Am J Kidney Dis 2001; 37(1):E7.
10.        Donat SM, Genega EM, Herr HW, Reuter VE: Mechanisms of prostatic stromal invasion in patients with bladder cancer: clinical significance. J Urol 2001;165: 1117-1120.
11.        Dalbagni G, Genega E, Zhang Z-F, Hashibe M, Russo P, Herr H, Reuter V: Radical cystectomy for bladder cancer: a contemporary series. J Urol 2001; 165: 1111-1116.
12.        Porter CR, O’Donnell C, Crawford DE, Gamito EJ, Errejon A, Genega E, Sotelo T, Tewari A: Artificial neural network model to predict biochemical failure following radical prostatectomy. Mol Urol 2001; 5:159-162.
13.        Xu X, Genega EM, Nasuti JF: Differential immunocytochemical staining patterns of uroplakin observed on neoplastic and non-neoplastic tissue fragments obtained from upper urinary tract brush specimens. Acta Cytologica 2002; 46:684-689.
14.        McHale T, Malkowicz SB, Tomaszewski JE, Genega EM: Potential pitfalls in the frozen section evaluation of parenchymal margins in nephron-sparing surgery. Am J Clin Pathol 2002; 118: 903-910.
15.        Genega EM, Porter CR. Urothelial neoplasms of the kidney and ureter. An epidemiologic, pathologic, and clinical review. Am J Clin Pathol. 2002; 117 Suppl: S36-48. Review.
16.        Carucci LR, Tirkes AT, Pretorius ES, Genega EM, Weinstein SP. Testicular Leydig cell hyperplasia: MR and ultrasound findings AJR Am J Roentgenol. 2003; 180(2): 501-3.
17.        Zhang PJ, Genega, EM, Tomaszewski JE, Pasha TL, LiVolsi VA: The role of calretinin, inhibin, Melan-A, bcl-2 and C-KIT, in differentiating adrenal cortical and medullary tumors, an immunohistochemical study. Mod Pathol. 2003; 16(6): 591-7.
18.        Seethala RR, Tirkes AT, Weinstein S, Tomaszewski JE, Malkowicz SB, Genega EM. Diffuse fibrous pseudotumor of the testicular tunics associated with an inflamed hydrocele. Arch Pathol Lab Med. 2003; 127(6): 742-4.
19.        Lee CT, Genega EM, Hutchinson B, Fearn PA, Kattan MW, Russo P, Reuter VE. Conventional (clear cell) renal carcinoma metastases have greater bcl-2 expression than high-risk primary tumors. Urol Oncol. 2003; 21(3): 179-84.
20.        Parwani AV, Kronz JD, Genega EM, Gaudin P, Chang S, Epstein JI. Prostate carcinoma with squamous differentiation. An analysis of 33 cases. Am J Surg Pathol. 2004; 28:651-657.
21.        Kuten A, Olumi A, Goldsmith J, Monahan-Early RA, Dvorak AM, Genega EM. Pathologic quiz case. A symptomatic renal tumor. Juxtaglomerular cell tumor. Arch Pathol Lab Med 2004; 128: e112-114.
22.        Genega EM, Kapali M, Torres-Quinnones M, Huang WC, Knauss JS, Wang L-P, Raghunath PN, Kozlowski C, Malkowicz SB, Tomaszewski JE. Impact of the 1998 World Health Organization/International Society of Urological Pathology classification system for urothelial neoplasms of the kidney. Mod Pathol. 2005; 18: 11-18.
23.        Porter CR, Latchamsetty KC, Genega EM. Urothelial neoplasms of the kidney and ureter: an epidemiologic, pathologic and clinical review. American Urologic Association Update Series 2005; Volume 24, Lesson 10.
24.        Gaston SM, Soares MA, Siddiqui MM, Vu D, Lee JM, Goldner DL, Brice MJ, Shih JC, Upton MP, Perides G, Baptista J, :avin PT, Bloch BN, Genega EM, Rubin MA, Lenkinski RE. Tissue-print and print-phoresis as platform technologies for the molecular analysis of human surgical specimens: mapping tumor invasion of the prostate capsule. Nat Med. 2005; 11: 95-101.
25.        Adey GS, Genega EM, Pedrosa I, Olumi AF. Upper urinary tract carcinoma: transitional or renal cell? Issues In Urol 2006; 18: 234-238.
26.        Pedrosa I, Chou M, Ngo L, Baroni R, Genega EM, Galaburda L, Dewolf WC, Rofsky NM. MR classification of malignant renal masses with pathologic correlation. Eur Radiol. 2008; 18: 365-375.
27.        Pedrosa I, Sun MR, Spenser M, Genega, EM, Olumi AF, Dewolf WC, Rofsky NM.  MR Imaging of renal masses: correlation with findings at surgery and pathology. RadioGraphics. 2008; 28: 985-1003.
28.        Mosquera JM, Perner S, Genega EM, Sanda M, Hofer MD, Mertz KD, Paris PL, Simko J, Bismar TA, Ayala G, Shah RB, Loda M, Rubin MA. Characterization of TMPRSS2-ERG fusion high-grade prostatci intraepithelial neoplasia and potential clinical implications. Clin Cancer Res. 2008; 14: 3380-3385.
29.        Lenkinski RE, Bloch BN, Liu F, Frangioni JV, Perner S, Rubin MA, Genega E, Rofsky NM, Gaston SM. An illustration of the potential for mapping MRI/MRS parameters with genetic over-expression profiles in human prostate cancer. MAGMA Magnetic Resonance Materials in Physics, Biology and Medicine (in press).

Ongoing Research Support
1. 1R01CA116465-01A2 (Neil Rofsky, M.D.)                     9/26/06-7/31/10
NIH
Characterization of Prostate Cancer with 3T MR Imaging.
Major goal: The purpose of this study is to investigate high resolution, dynamic 3D MRI, MRS and T2 weighted imaging at 3T for determining tumor volume, tumor stage and tumor grade using whole mount histopathology as the reference standard for comparison.
Role: Co-Investigator.

2.    U01CA11391-01 (Martin Sanda, M.D.)                                   3/29/05-04/28/10
NIH
Harvard/Michigan Prostate Cancer Biomarker Clinical Center (an EDNR-CEVC).
Major goal: To evaluate biomarkers for prostate cancer early detection.
Role: Co-Investigator.